The Klondike Highway links the Alaskan coastal town of Skagway to Yukon's Dawson City and its route somewhat parallels that used by prospectors in the 1898 Klondike Gold Rush.

It winds in the state of Alaska for 24 km (15 miles), up through the White Pass in the Coast Mountains where it crosses the Canadian border to British Columbia (BC) for 56 km, then enters Yukon where it reaches the Alaska Highway near Whitehorse and shares a short section with that highway until north of Whitehorse, where it diverges once more to Dawson City. The highway is 712 km (443 miles) long.